ETC Group renewed its call for a moratorium on the release and commercialization of synthetic organisms, asserting that societal debate on the oversight of synthetic biology is urgently overdue. The renewed call came as J. Craig Venter’s research team announced that it has constructed a bacterial-length synthetic genome in the lab using mail-order synthetic DNA sequences. They’ve named the synthetic genome, Mycoplasma genitalium JCVI-1.0, and it’s similar to its counterpart in nature, a genital bacterium with the smallest known genome of any free living organism. The announcement is not breaking news because the work had been previously reported, but the details were published today in Science.
Recent Content Related to Synthetic Biology
In the name of moving “beyond petroleum,” Big Oil, Gene Giants, governments, start-ups and others are forming partnerships that will extend corporate control over more resources in every part of the globe – while keeping the root causes of climate change intact. With grudging recognition that first-generation agrofuels are neither economical nor ecological, investors turn to other life-based technologies, including synthetic biology, for the next alternative fuel fix.
A report on policy options for governance of synthetic biology is a disappointing effort that fails to address wider societal concerns about the rapid deployment of a powerful and controversial new technology. Synthetic biology aims to commercialize new biological parts, devices and living organisms that are constructed from synthetic DNA - including dangerous pathogens. Synthetic biologists are attempting to harness cells as tiny factories for industrial production of chemicals, including pharmaceuticals and fuels. ETC Group describes the synthetic biology approach as "extreme genetic engineering."
Scientists and industrialists in the controversial new field of synthetic biology (building life-forms from scratch) are meeting in Zurich, Switzerland this week amidst claims that the world’s first entirely human-made organism may be only weeks away from creation. Swiss and international civil society groups are calling for swift action to control this technology but the scientists themselves are advancing pre-emptive proposals to evade regulation. As scientists meet in Zurich, the UK’s Royal Society and the Swiss government announce plans to investigate synthetic biology.
Synthetische Biologie beinhaltet die künstliche – oder eben synthetische – Herstellung von Genen, Lebewesen oder Teilen davon. Es ist ein neues Feld extremer Gentechnik.
Vom 24. bis 26. Juni 2007 fand an der ETH Zürich der dritte weltweite Kongress zur Synthetischen Biologie statt. Schweizerische und internationale Organisationen fordern die Regierungen zu schnellem Handeln auf, um diese neue und potentiell gefährliche Technologie zu regulieren und zu kontrollieren.
Ten years after Dolly the cloned sheep made her stunning debut, the J. Craig Venter Institute is applying for a patent on a new biological bombshell - the world's first-ever human-made species. The novel bacterium is made entirely with synthetic DNA in the laboratory.
Synthia, the (theoretical) human-made synthetic microbe – still barely a twinkle in J. Craig Venter’s eye – may be in search of a surrogate micro-mom sometime very soon. According to a research report released today in Science magazine, Synthia (the subject of a patent application discovered by ETC Group a few weeks ago -see “Goodbye Dolly -- Hello Synthia!”) may have overcome her last hurdle. The report, authored by Craig Venter and his colleagues at Synthetic Genomics Inc., claims to have inserted a foreign bacterial genome into the cell of another bacterial species. Nobel laureate Hamilton Smith who is one of Venter’s co-authors in the research article told a meeting of synthetic biologists in Zürich on Monday that this represents a significant step en route to building a whole new life form. As the article itself concludes, “…we have discovered a form of bacterial DNA transfer that permits … recipient cells to be platforms for the production of new species using modified natural genomes or manmade genomes…”
A new report by the ETC Group concludes that the social, environmental and bio-weapons threats of synthetic biology surpass the possible dangers and abuses of biotech. The full text of the 70-page report, Extreme Genetic Engineering: An Introduction to Synthetic Biology, is available for downloading free-of-charge on the ETC Group website.
"Genetic engineering is passé," said Pat Mooney, Executive Director of ETC Group. "Today, scientists aren't just mapping genomes and manipulating genes, they're building life from scratch - and they're doing it in the absence of societal debate and regulatory oversight," said Mooney.
Issue: Medical applications of nano-scale technologies have the potential to revolutionize healthcare by delivering powerful tools for diagnosing and treating disease at the molecular level. But the current zeal for nano-enabled
medicines could divert scarce medical R&D funds away from essential health services and direct resources away from non-medical aspects of community health and wellbeing. Although nanomedicine is being touted as a solution to pressing health needs in the global South, it is being driven from the North and is designed primarily for wealthy markets. Using nano-scale technologies, the pharmaceutical industry’s ultimate goal is to make every person a patient and every patient a paying customer by “medicating” social ills with human performance enhancement (HyPE) drugs and devices. Nanoenabled HyPEs could usher in an era of two-tiered humans – Homo sapiens and Homo sapiens 2.0.
Synthetic biology (the attempt to create artificial living organisms) should be self-regulated say scientists at Berkeley assembly. Civil Society organizations say "No!"
"If biologists are indeed on the threshold of synthesizing new life forms, the scope for abuse or inadvertent disaster could be huge." Nature, October 2004
Scientists working at the interface of engineering and biology - in the new field of "synthetic biology" - worry that public distrust of biotechnology could impede their research or draw attention to regulatory chasms. Synthetic biologists are trying to design and construct artificial living systems to perform specific tasks, such as producing pharmaceutical compounds or energy. In October 2004, the journal Nature warned, "if biologists are indeed on the threshold of synthesizing new life forms, the scope for abuse or inadvertent disaster could be huge." An editorial in that same issue suggested that there may be a need for an "Asilomar"-type conference on synthetic biology. In light of these concerns, scientists gathering at "Synthetic Biology 2.0" (May 20-22, 2006) at the University of California-Berkeley hope to make "significant progress" toward a "code of ethics and standards." Their actions are intended to project the message that the synthetic biologists are being pro-active and capable of governing themselves as a "community." In their view, self-governance is the best way forward to safely reap the benefits (both societal and financial) of synthetic biology. Civil Society organizations disagree.
A coalition of thirty-eight international organizations including scientists, environmentalists, trade unionists, biowarfare experts and social justice advocates called for inclusive public debate, regulation and oversight of the rapidly advancing field of synthetic biology - the construction of unique and novel artificial life forms to perform specific tasks. Synthetic biologists are meeting this weekend in Berkeley, California where they plan to announce a voluntary code of self-regulation for their work (1). The organizations signing the Open Letter are calling on synthetic biologists to abandon their proposals for self-governance and to engage in an inclusive process of global societal debate on the implications of their work (see attached Open Letter).